First, add a little bit of oil to a large skillet and brown the sausage and onion over medium high heat. Lightly season with salt and pepper and let it cool.
Now in a large bowl add the Bisquick, shredded cheese, Parmesan, milk, mayonnaise, egg, salt, pepper, garlic powder and the cooked sausage and onions. Then stir everything together until it’s evenly combined.
After that, spray a loaf pan with cooking spray and place the sausage bread mixture inside. Now spread it evenly into the pan.
Bake it at 350° for 50 minutes then take it out of the oven to cool in the loaf pan for about 10 minutes.
Finally, remove the sausage bread from the loaf pan and slice it. Serve warm and enjoy!